86 research outputs found

    Health, Safety, Environment and Ergonomic Improvement in Energy Sector Using an Integrated Fuzzy Cognitive Map–Bayesian Network Model

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    © 2018, Taiwan Fuzzy Systems Association and Springer-Verlag GmbH Germany, part of Springer Nature. Health, safety, environment and ergonomics (HSEE) are important factors for any organization. In fact, organizations always have to assess their compliance in these factors to the required benchmarks and take proactive actions to improve them if required. In this paper, we propose a fuzzy cognitive map–Bayesian network (BN) model in order to assist organizations in undertaking this process. The fuzzy cognitive map (FCM) method is used for constructing graphical models of BN to ascertain the relationships between the inputs and the impact which they will have on the quantified HSEE. Using the notion of Fuzzy logic assists us to work with humans and their linguistic inputs in the process of experts’ opinion solicitation. The noisy-OR method and the EM are used to ascertain the conditional probability between the inputs and quantifying the HSEE value. Using this, we find out that the most influential input factor on HSEE quantification which can then be managed for improving an organization’s compliance to HSEE. Finding the same influential input factor in both BN models which are based on the noisy-OR method and EM demonstrate how FCM is useful in constructing a reliable BN model. Leveraging the power of Bayesian network in modelling HSEE and augmenting it with FCM is the main contribution of this research work which opens the new line of research in the area of HSE management

    EFFECT OF DIET DILUTION IN THE STARTER PERIOD ON PERFORMANCE AND CARCASS CHARACTERISTICS OF BROILER CHICKS

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    The effect of energy and protein dilution in the starter period (8 to 14 days) of age, on performance and carcass characteristics of 360 Arian male chicks was studied in a completely randomised design. This experiment consisted of 6 treatments, 4 replicates, with 15 chicks per replicate. In order to dilute the diets six levels (0, 4, 8, 12, 16, and 20) percent of ground wood charcoal was used. Chicks were fed with starter and grower diet from 15 to 21 and 22 to 42 days of age respectively. During the experiment feed intake, body weight gain, feed conversion ratio were measured weekly. Mortality was measured throughout the experiment. At 43 day of age 4 chicks each treatment was selected and carcass characteristics were measured. The results indicated that dilution of diet from 8 to 14 days of age increased feed intake in this period but the differences were not signifi cant. With increasing dilution rate body weight gain of chicks signifi cantly decreased in comparison to control group (P< 0.05). Due to compensatory growth after restricted period, there was not signifi cant difference in body weight among restricted and control groups at 42 days of age. There was not signifi cant difference among the treatments for feed conversion ratio in whole period of the experiment (8 to 42 day). Similarly, there was not signifi cant difference among the treatments for caloric conversion ratio in whole period of the experiment (8 to 42 day). Mortality rate in restricted groups was signifi cantly lower than control group (P<0.05). Diet dilution hadn’t signifi cant effect on carcass, breast meat, drumsticks, thighs, liver, intestine, abdominal fat percentages. The results of the present study indicated that broiler chicks could withstand a 7-day period (from 8 to 14 days) feed restriction with ground wood charcoal in early age without loss in performance

    Developing criteria for Cesarean Section using the RAND appropriateness method

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    <p>Abstract</p> <p>Background</p> <p>Cesarean section rates are increasing worldwide, and a rapid increase has been observed in Iran. Disagreement exists between clinicians about when to use cesarean section. We aimed to identify the appropriateness criteria for the use of cesarean section in Iran.</p> <p>Method</p> <p>A consensus development study using a modified version of the RAND Appropriateness Method (RAM). We generated scenarios from valid clinical guidelines and expert opinions. A panel of experts participated in consensus development: first round via mail (12 members), second round face-to-face (9 members). We followed the RAM recommendations for the development of the scenario lists, rating scales, and statistical analyses.</p> <p>Results</p> <p>294 scenarios relevant to cesarean section were identified. 191 scenarios were considered appropriate, of which 125 scenarios were agreed upon. The panel found cesarean inappropriate for 21% of scenarios, and 'equivocal' for 14% of scenarios.</p> <p>Conclusion</p> <p>RAM is useful for identifying stakeholder views in settings with limited resources. The participants' views on appropriateness of certain indications differed with available evidence. A large number of scenarios without agreement may partly explain why it has been difficult to curb the growth in cesarean section rate.</p

    "A Survey about Knowledge and Attitudes of People towards Violence against Women in Community/ Family Settings"

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    In this article a very brief history of violence against women in domestic settings is developed. On the whole, 18 Focus group discussion (FGD) (including 4 pilot FGDs), were conducted in southern part of Teheran Capital of Iran among different groups of people (literate, illiterate, married, unmarried, male, female). Further, 30 individual interviews conducted with violence and family affaire experts such as police, forensic medicine experts, psychologists, social-workers, authorities, judges, and sociologists. Findings demonstrated a very traditional problem-solving approach to violence and violence-based issues. Moreover, violence is sometimes justified by natural superiority of men to women. It is also considered as a necessity for some purposes and therefore, it is accepted and may continue to exist among families and community for coming years. Public and private spheres are almost genderly divided and formal institutions and organizations are tried to be kept away from family violence related issues. This is mainly because of a belief that domestic violence belongs to private sphere rather than public one

    A new pillared Cd-organic framework as adsorbent of organic dyes and as precursor of CdO nanoparticles

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    A new neutral cadmium-organic framework with a pillared layer structure, [Cd3(BTC)2(4-bpdb)2] (H3BTC = benzene-1,3,5-tricarboxylic acid; 4-bpdb = 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene), has been synthesized via solvothermal reaction of cadmium nitrate with the tricarboxylic acid H3BTC and the linear bispyridyl linker 4-bpdb. The complex has been characterized by single crystal X-ray diffraction, showing to possess a 3D porous network of jcr7 topology. The capability of the prepared MOF in adsorbing the organic dyes Congo Red (CR) and Neutral Red (NR), together with kinetics and thermodynamics of their adsorption, have been investigated in detail. The adsorption process was well described by pseudo-first order and pseudo-second order kinetics for CR and NR, respectively. In addition, conversion of the MOF 3D architecture into nano-sized cadmium oxide particles has also been studied

    Orexin-2 receptor antagonism in the cornu ammonis 1 region of hippocampus prevented the antinociceptive responses induced by chemical stimulation of the lateral hypothalamus in the animal model of persistent pain

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    Orexins are excitatory neuropeptides, mainly produced by neurons located in the lateral hypothalamus, which project to many brain areas. The orexinergic system plays a fundamental role in arousal, sleep/wakefulness, feeding, energy homeostasis, motivation, reward, stress and pain modulation. As a prominent part of the limbic system, the hippocampus has been involved in formalin-induced nociception modulation. Moreover, hippocampus regions express both orexin-1 (OX1) and orexin-2 (OX2) receptors. The present study investigated the role of OX2 receptors (OX2R) within the cornu ammonis 1 (CA1) region of the hippocampus in the mediation of lateral hypothalamus-induced antinociception. Fifty-three male Wistar rats were unilaterally implanted with two separate cannulae into the lateral hypothalamus and CA1. Animals were pretreated with intra-CA1 TCS OX2 29 as an OX2R antagonist before intra-lateral hypothalamus administration of carbachol (250 nM) as a muscarinic agonist for chemical stimulation of orexinergic neurons. Formalin test was used as an animal model of persistent pain, following intra-lateral hypothalamus carbachol microinjection. Results showed that the chemical stimulation of the lateral hypothalamus significantly attenuated formalin-evoked nociceptive behaviors during both phases of the formalin test, and administration of TCS OX2 29 into the CA1 blocked these antinociceptive responses in both phases, especially in the late phase. These findings suggest that OX2 receptors in the CA1 partially mediate the lateral hypothalamus-induced antinociceptive responses in persistent inflammatory pai

    Next-generation sequencing reveals a novel pathological mutation in the TMC1 gene causing autosomal recessive non-syndromic hearing loss in an Iranian kindred

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    OBJECTIVES: Hearing loss (HL) is the most common sensory-neural disorder with excessive clinical and genetic heterogeneity, which negatively affects life quality. Autosomal recessive non-syndromic hearing loss (ARNSHL) is the most common form of the disease with no specific genotype-phenotype correlation in most of the cases. Whole exome sequencing (WES) is a powerful tool to overcome the problem of finding mutations in heterogeneous disorders. METHODS: A comprehensive clinical and pedigree examination was performed on a multiplex family from Khuzestan province suffering from hereditary HL. Direct sequencing of GJB2 and genetic linkage analysis of DFNB1A/B was accomplished. WES was utilized to find possible genetic etiology of the disease. Co-segregation analysis of the candidate variant was done. High resolution melting analysis was applied to detect variant status in 50 healthy matched controls. RESULTS: Clinical investigations suggested ARNSHL in the pedigree. The family was negative for DFNB1A/B. WES revealed a novel nonsense mutation, c.256G > T (p.Glu86*), in TMC1 segregating with the phenotype in the pedigree. The variant was absent in the controls. CONCLUSION: Here, we report successful application of WES to identify the molecular pathogenesis of ARNSHL in a large family. The novel nonsense TMC1 variant meets the criteria of being pathogenic according to the ACMG-AMP variant interpretation guidelin
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